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Citalopram®

Citalopram is FDA apprved for treatment of major depressive disorder.

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Common Dosage:

20 mg once daily with or without food

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Common Side Effects

Most common side effect are agitation, confusion, fast heart beat (Serotonin Syndrome), heart rhythm problem, low sodium levels, eye problems, delayed ejaculation

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citalopram tablets may cause serious side effects, including:

Increased risk of suicidal thoughts and actions. Citalopram tablets and other antidepressant medicines may increase suicidal thoughts and actions in some children, adolescents, and young adults especially within the first few months of treatment or when the dose is changed. Citalopram tablets are not for use in children.
Depression and other mental illnesses are the most important causes of suicidal thoughts and actions.

Pay close attention to any changes, especially sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions. This is very important when an antidepressant medicine is started or when the dose is changed.  
Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.  
Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.   
Call your healthcare provider or get emergency medical help right away if you or your family member have any of the following symptoms, especially if they are new, worse, or worry you:
thoughts about suicide or dying
new or worse depression
feeling very agitated or restless
trouble sleeping (insomnia) 
acting aggressive, being angry, or violent  
an extreme increase in activity or talking (mania) 
attempts to commit suicide
new or worse anxiety
acting on dangerous impulses
panic attacks
new or worse irritability
other unusual changes in behavior or mood

Citalopram tablets are a prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD) in adults.  

It is not known if citalopram tablets are safe and effective for use in children.

Do not take citalopram tablets if you:
take a Monoamine Oxidase Inhibitor (MAOI) 
have stopped taking an MAOI in the last 14 days 
are being treated with the antibiotic linezolid or intravenous methylene blue
take pimozide
are allergic to citalopram or any of the ingredients in citalopram tablets. See the end of this Medication Guide for a complete list of ingredients in citalopram tablets.
Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.   

Do not start taking an MAOI for at least 14 days after you stop treatment with citalopram tablets.

have or have a family history of suicide, depression, bipolar disorder, mania or hypomania
have an abnormal heart rhythm called QT prolongation
have or had heart problems, including a heart attack, heart failure, abnormal heart rhythm, or long QT syndrome
have low potassium, magnesium, or sodium levels in your blood 
have or had bleeding problems
have or had seizures (convulsions)
have high pressure in the eye (glaucoma)
have or had kidney or liver problems
are pregnant or plan to become pregnant. Citalopram tablets may harm your unborn baby. Taking citalopram tablets late in pregnancy may lead to an increased risk of certain problems in your newborn. Talk to your healthcare provider about the risks and benefits of treating depression during pregnancy. 
Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with citalopram tablets.
There is a pregnancy registry for females who are exposed to citalopram tablets during pregnancy. The purpose of the registry is to collect information about the health of females exposed to citalopram tablets and their baby. If you become pregnant during treatment with citalopram tablets, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants. You can register by calling 1-844-405-6185 or visiting online at https://womensmentalhealth.org/research/pregnancyregistry/antidepressants. 
are breastfeeding or plan to breastfeed. It is not known if citalopram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with citalopram tablets. 
If you breastfeed during treatment with citalopram tablets, call your healthcare provider right away if your baby develops sleepiness or fussiness, or is not feeding or gaining weight well. 
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.  

Citalopram tablets and other medicines may affect each other causing possible serious side effects. Citalopram tablets may affect the way other medicines work and other medicines may affect the way citalopram tablets works.  

Especially tell your healthcare provider if you take:  
medicines used to treat migraine headaches known as triptans
tricyclic antidepressants
lithium
tramadol, fentanyl, meperidine, methadone, or other opioids
tryptophan
buspirone
amphetamines
St. John’s Wort
medicines that can affect blood clotting such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) and warfarin
diuretics 
methadone
gatifloxacin or moxifloxacin
medicines used to control your heart rate or rhythm (antiarrhythmics)
medicines used to treat mood, anxiety, psychotic or thought disorders, including selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs)
Ask your healthcare provider if you are not sure if you are taking any of these medicines. Your healthcare provider can tell you if it is safe to take citalopram tablets with your other medicines.

Do not start or stop any other medicines during treatment with citalopram tablets without talking to your healthcare provider first. Stopping citalopram tablets suddenly may cause you to have serious side effects. See, “What are the possible side effects of citalopram tablets?”  

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

Take citalopram tablets exactly as your healthcare provider tells you to take it. Do not change your dose or stop taking citalopram tablets without first talking to your healthcare provider. 
Your healthcare provider may need to change the dose of citalopram tablets until it is the right dose for you.
Take citalopram tablets 1 time each day with or without food.
If you take too much citalopram tablets, call your healthcare provider or poison control center at 1-800-222-1222, or go to the nearest hospital emergency room right away.

Citalopram tablets may cause serious side effects, including:
Heart rhythm problems. Citalopram tablets may cause a serious change in your heartbeat (a fast or irregular heartbeat) that may cause death. Tell your healthcare provider right away if you feel faint or pass out, or if you have a change in your heart beat.
Serotonin syndrome.  Taking citalopram tablets can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when citalopram tablets is taken with certain other medicines. See, “Who should not take citalopram tablets?” Call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome: 
agitation
confusion
fast heart beat
dizziness
flushing 
tremors, stiff muscles, or muscle twitching 
seizures
seeing or hearing things that are not real (hallucinations)
coma
blood pressure changes
sweating
high body temperature (hyperthermia)
loss of coordination
nausea, vomiting, diarrhea 
Increased risk of bleeding. Taking citalopram tablets with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), warfarin or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
Manic episodes. Manic episodes may happen in people with bipolar disorder who take citalopram tablets. Symptoms may include:
greatly increased energy 
racing thoughts
unusually grand ideas 
talking more or faster than usual 
severe trouble sleeping
reckless behavior 
excessive happiness or irritability
Discontinuation syndrome. Suddenly stopping citalopram tablets may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include: 
nausea
changes in your mood
irritability and agitation
dizziness
electric shock sensation (paresthesia)
anxiety
confusion  
sweating
headache
tiredness
problems sleeping
hypomania
ringing in your ears (tinnitus)
seizures
Seizures (convulsions).
Eye problems (angle-closure glaucoma). Many antidepressant medicines, including citalopram tablets, may cause a certain type of eye problem called angle-closure glaucoma. Call your healthcare provider if you have changes in your vision or eye pain.
Low sodium levels in your blood (hyponatremia). Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this. Tell your healthcare provider right away if you develop any signs or symptoms of low sodium levels in your blood during treatment with citalopram tablets. Signs and symptoms of low sodium levels in your blood may include:
headache
memory changes
weakness and unsteadiness on your feet which can lead to falls 
difficulty concentrating
confusion
In severe or more sudden cases, signs and symptoms include:
hallucinations (seeing or hearing things that are not real) 
seizures
stopping breathing
fainting
coma
death

Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SSRIs), including citalopram tablets, may cause sexual problems.
Symptoms in males may include:
Delayed ejaculation or inability to have an ejaculation
Decreased sex drive
Problems getting or keeping an erection
Symptoms in females may include:
Decreased sex drive
Delayed orgasm or inability to have an orgasm
Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with DRIZALMA SPRINKLE. There may be treatments your healthcare provider can suggest.  

The most common side effect of citalopram tablets is delayed ejaculation.

These are not all the possible side effects of citalopram tablets.  

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Store citalopram tablets at room temperature between 68°F to 77°F (20°C to 25°C).
Keep citalopram tablets and all medicines out of the reach of children.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use citalopram tablets for a condition for which it was not prescribed. Do not give citalopram tablets to other people, even if they have the same symptoms that you have. It may harm them. You may ask your healthcare provider or pharmacist for information about citalopram tablets that is written for healthcare professionals.  

Active ingredient: citalopram hydrobromide

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